The effect of serum proteins on dynamic interfacial properties of silicone oils in vitrectomized eyes
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How to Cite

1.
Nepita I, Liggieri L, Santini E, Ravera F, Romano MR, Pralits JO, Repetto R. The effect of serum proteins on dynamic interfacial properties of silicone oils in vitrectomized eyes. MAIO [Internet]. 2018 Jun. 18 [cited 2022 Jun. 25];2(2):52-7. Available from: https://www.maio-journal.com/index.php/MAIO/article/view/72

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Keywords

emulsion; silicone oil; surface tension; vitrectomy

Abstract

The formation and stability of emulsions in vitrectomized eyes is linked to the properties of the silicone oil-aqueous humor interface, in particular the surface tension. In the presence of natural surfactants, such as serum and plasma, the value of the surface tension is likely to change, but little quantitative information is presently available.

To this end, we perform accurate experiments measuring the interfacial
properties of the Siluron 1000 (Fluoron GmbH, Ulm, Germany) silicone oil with an aqueous solution in the presence of endogenous-like proteins. It is found that the surface tension is significantly reduced when physiologically realistic concentrations are used. Moreover, the values obtained for the dilational viscoelastic modulus are compatible with the formation of stable emulsions.

https://doi.org/10.35119/maio.v2i2.72
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References

Nakamura K, Refojo MF, Crabtree DV. Factors contributing to the emulsification of intraocular silicone and fluorosilicone oils. Invest Ophthalmol Visual Sci.1990;31(4):647-656.

Caramoy A, Hagedorn N, Fauser S, Kugler W, Groß T, Kirchhof B. Development of emulsification-resistant silicone oils: can we go beyond 2000 mPas silicone oil?. Invest Ophthalmol Visual Sci.2011;52(8):5432-5436.

Zelisko PM, Flora KK, Brennan JD, Brook MA. Water-in-silicone oil emulsion stabilizing surfactants formed From native albumin and α, ω-triethoxysilylpropyl-polydimethylsiloxane. Biomacromolecules. 2008;9(8);2153-2161.

Loglio G, Pandolfini P, Miller R, Makievski AV, Ravera F, Ferrari M, Liggieri L. Novel methods to study interfacial layers. Stud Interface Sci. 2001;11:439.

Ravera F, Ferrari M, Santini E, Liggieri L. Influence of surface processes on the dilational visco-elasticity of surfactant solutions. Adv Colloid Interface Sci. 2005;117(1-3):75-100.

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