Polarimetric interferometry to objectively evaluate the optical properties of corneal stroma

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Lipari E, Sborgia A, Nubile M, Mastropasqua L, Alessio G. Polarimetric interferometry to objectively evaluate the optical properties of corneal stroma. MAIO [Internet]. 2018 Jun. 18 [cited 2024 May 22];2(2):36-41. Available from: https://www.maio-journal.com/index.php/MAIO/article/view/69

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birefringence; corneal cross; isogyre; melatope


A new non-invasive method, based on the interferometric analysis of diff ractive and polarizing effects related to the birefringent properties of corneal collagen fibrils, has been developed to objectively evaluate the optical properties of the stroma. The new method shows a relevant impact on corneal surgeries specifically for lamellar transplantation where, due to the polarizing properties of the stroma, the alignment between collagen fibrils of donor corneas with patient collagen fibril orientation has shown an improvement of visual acuity postoperatively. Further studies on the regularity of the corneal isogyre pattern are showing this new method has a strong impact in early-stage diagnosis of corneal disease.



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